A NOVEL FEEDBACK LOOP BETWEEN HIGH MALAT-1 AND LOW MIR-200C-3P PROMOTES CELL MIGRATION AND INVASION IN PANCREATIC DUCTAL ADENOCARCINOMA AND IS PREDICTIVE OF POOR PROGNOSIS

A novel feedback loop between high MALAT-1 and low miR-200c-3p promotes cell migration and invasion in pancreatic ductal adenocarcinoma and is predictive of poor prognosis

Abstract Background It was demonstrated that long non-coding RNAs occupied an important position in tumor pathogenesis and progression.We have previously found that the metastasis-associated lung adenocarcinoma transcript 1 (MALAT-1) promotes cell proliferation and metastases in pancreatic ductal adenocarcinoma (PDAC).The present study was aimed to

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The Game Is Not over Yet—Go in the Post-AlphaGo Era

The game of Go was the last great challenge for artificial intelligence in abstract board games.AlphaGo was the first system to reach supremacy, and subsequent implementations further improved the state of the art.As in chess, the fall of the human world champion did not lead to the end of the game.Now, we have renewed interest in the game due to n

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Theorizing and Social Gerontology

Theory is increasingly important in social gerontology.Thus it is gratifying to see the debut of a new journal that encourages theorizing about age and aging.The papers in Volume 1, number 1 of the International Journal of Ageing and Later Latest Product Releases & Innovations – Stay Updated! Life reflect a concern for developing theory that is l

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